Respuestas
Respuesta:
of evidence. Levels of evidence and grades of recommendation from
current use
There are multiple proposals and classifications that hierarchize evidence, which may confuse those who are
dedicated to generate it both in health technology assessments, as for the development of clinical guidelines,
etc. The aim of this manuscript is to describe the most commonly used classifications of levels of evidence and
grades of recommendation, analyzing their main differences and applications so that the user can choose the one
that better suits your needs and take this health decisions basing their practice on the best available evidence.
A systematic literature search was performed in PubMed and MEDLINE databases and in Google, Yahoo and
Ixquick search engines. A wealth of information concerning levels of evidence and degrees recommendation
was obtained. It was summarized the information of the 11 proposals more currently used (CTFPHC, Sackett,
USPSTF, CEBM, GRADE, SIGN, NICE, NHMRC, PCCRP, ADA y ACCF/AHA), between which it emphasizes
the GRADE WORKING GROUP, incorporated by around 90 national and international organizations such as the
World Health Organization, The Cochrane Library, American College of Physicians, American Thoracic Society,
UpToDate, etc.; and locally by the Ministry of Health to create clinical practice guidelines.
Key words: “Evidence-Based Practice”[Mesh], “Evidence-Based Medicine”, levels of evidence, grades of
recommendation, clinical recommendation.
Palabras clave: Práctica clínica basada en la evidencia; medicina basada en la evidencia niveles de evidencia,
grados de recomendación, recomendación clínica.
Explicación: