Respuestas
Respuesta:
ASDAS-CRP (Ankylosing Spondylitis Disease Activity Score)
Assess disease activity in Ankylosing Spondylitis.
Back Pain Severity? (Rate From 0-10)
Ask "How would you describe the overall level of AS neck, back or hip pain you have had?"
Unanswered
Duration of Morning Stiffness? (Rate From 0-10)
Ask "How long does your morning stiffness last from the time you wake up?"
Unanswered
Patient Global Assessment of Disease Activity? (Rate From 0-10)
Unanswered
Peripheral Pain/Swelling? (Rate From 0-10)
Ask "How would you describe the overall level of pain/swelling in joints other than neck, back or hips you have had?"
Unanswered
CRP?
Unanswered
nmol/L
Results
Please answer all questions. The results will be computed once all questions are answered.
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About this tool
The Ankylosing Spondylitis Disease Activity Score (ASDAS) is an index to assess disease activity in Ankylosing Spondylitis (AS).
The prefered score uses CRP, rather than ESR.
ASDAS-CRP =0.12 x Back Pain + 0.06 x Duration of Morning Stiffness + 0.11 x Patient Global + 0.07 x Peripheral Pain/Swelling + 0.58 x Ln(CRP+1)
ASDAS-ESR = 0.08 x Back Pain + 0.07 x Duration of Morning Stiffness + 0.11 x Patient Global + 0.09 x Peripheral Pain/Swelling + 0.29 x â(ESR)
Back pain, patient global assessment, duration of morning stiffness and peripheral pain/swelling are all assessed on a numerical rating scale (from 0 to 10).
The 3 cut-offs selected to separate these states (figure 1) were: <1.3 between "inactive disease" and "moderate disease activity", <2.1 between "moderate disease activity" and "high disease activity", and >3.5 between "high disease activity" and "very high disease activity".
Cut-offs for improvement scores were: a change ≥1.1 units for "clinically important improvement" and a change ≥2.0 units for "major improvement".
References
Nukas C, Landewé R, Sieper J, Dougados M, Davis J, Braun J, van der Linden S, van der Heijde D.
Development of an ASAS-endorsed disease activity score (ASDAS) in patients with ankylosing spondylitis.
Ann Rheum Dis 2009;68:18-24.
van der Heijde D, Lie E, Kvien TK, Sieper J, van den Bosch F, Listing J, Braun J, Landewé R.
ASDAS, a highly discriminatory ASAS-endorsed disease activity score in patients with ankylosing spondylitis.
Ann Rheum Dis 2009;68:1811-8.
Machado P, Landewé R, Lie E, Kvien TK, Braun J, Baker D, van der Heijde D.
Ankylosing Spondylitis Disease Activity Score (ASDAS): defining cut-off values for disease activity states and improvement scores.
Ann Rheum Dis 2011, 70 (1): 47-53
Machado P, Landewé R, van der Heijde D.
Endorsement of the definitions of disease activity states and improvement scores for the Ankylosing Spondylitis Disease Activity Score (ASDAS): results from the Outcome Measures in Rheumatology (OMERACT) 10 conference.
J Rheumatol. 2011 Jul;38(7):1502-6.
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